You can life equal to its power." Then you could handle something like Emrakul, the Aeons Torn

Alloy Golem Altar Golem Basalt Golem Battered Golem Bosh, Iron Golem Bosh, Iron Golem Avatar Bottle Golems Boulderbranch Golem Clay Golem Coal Golem Cobalt Golem Composite Golem Crystal Golem Dross Golem Emblazoned Golem Enatu Golem Epitaph Golem Flint Golem Geode Golem Glass Golem Golem Artisan Golem Foundry Golem's Heart Golem-Skin Gauntlets Hematite Golem Hexplate Golem Howling Golem Icehide Golem Ichorplate Golem Igneous Golem Iron Golem Junk Golem Karn, Silver Golem Lead Golem Limestone Golem Lodestone Golem Malachite Golem Matopi Golem Meteor Golem Mirror Golem Mycosynth Golem Obsianus Golem Oxidda Golem Patagia Golem Pewter Golem Precursor Golem Razor Golem Reflective Golem Relic Golem Rusting Golem Saberclaw Golem Sand Golem Soldevi Golem Soultether Golem Sparring Golem Spire Golem Steel Golem Stone Golem Straw Golem Tangle Golem Thran Golem Titanium Golem Tribal Golem Ur-Golem's Eye Will-Forged Golem

The first commander that I thought of when I saw this card was Ardenn, Intrepid Archaeologist
A board wipe for five mana, Wave of Reckoning makes each creature deal damage to itself equal to its power
Gallery and List of Fuse Cards Alive // Well Armed // Dangerous Beck // Call Breaking // Entering Catch // Release Down // Dirty Far // Away Flesh // Blood Gallifrey Falls // No More Give // Take Profit // Loss Protect // Serve Ready // Willing Toil // Trouble Turn // Burn Wear // Tear Best Fuse Cards Beck / Call Similar to Glimpse of Nature, but with distinct differences, the Beck side of this card allows you to draw cards whenever creatures enter the battlefield, including your opponents cards