Purvalanol A - CAS# 212844-53-6 181 Chemical Name: 2-morpholino-4H-benzo[h]chromen-4-one

Chemical Name: 2-morpholino-4H-benzo[h]chromen-4-one

CAS Number: 774549-97-2

CAS Number: 348086-71-5

S3I-201 treatment of somatotroph tumor xenografts (n=15) significantly attenuated tumor growth for the duration of the experiment

84 L per h per kg body weight) and high oral bioavailability (37%)

Purvalanol A - CAS# 212844-53-6 181 Chemical Name: 2-morpholino-4H-benzo[h]chromen-4-onePurvalanol A, CAS No. 212844 53 6, is a potent CDK inhibitor, which effectively suppresses Src mediated transformation by inhibiting both CDKs and c Src. indicating that the activation of CDKs contributes to the c Src transformation. Purvalanol A suppressed the c Src activity as effectively as the Src selective inhibitor PP2, and that it reverted the transformed morphology to a nearly normal shape with less cytotoxicity than PP2. Purvalanol A induced