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Pratosartan is a selective angiotensin II receptor antagonist
In HEK 293 cells stably transfected with rat or human histamine H3 receptors
GW5074 and T-00127_HEV1 almost completely inhibit PI4KB kinase activity at 10 μM (3% and 5% of residual activity
pyroptosis and necroptosis) and inflammation
ClH/c1-2-16-8-4-6-13-21(16)24-15-18(23)14-22-20-12-7-10-17-9-3-5-11-19(17)20
N-Desmethyl-Apalutamide tenoic acid Pratosartan is a selective angiotensinN Desmethyl Apalutamide is an active metabolite of Apalutamide. N Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one third of the activity of Apalutamide. The formation of N Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma proteins bound concentration. Product information CAS Number:
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