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Smiles: CC(=O)OC(C)(C)C=CC(=O)C(C)(O)C1C(O)CC2(C)C3CC=C4C(C=C(O)C(=O)C4(C)C)C3(C)C(=O)CC21C
Formula: C16H22ClNO2
4R)-2-[(4R)-2-[2-(acetyloxy)-6-pentylphenyl]-4
but has minimal effect on viability of nontransformed human cells
10 mg/kg FR183998 via intravenous administration
CB1-IN-1 Catalog No.:M21313-C Smiles: CC(=O)OC(C)(C)C=CC(=O)C(C)(O)C1C(O)CC2(C)C3CC=C4C(C=C(O)C(=O)C4(C)C)C3(C)C(=O)CC21CCB1 IN 1 (BPRCB1184) is a peripherally restricted CB1R antagonist, with Ki of 0. 3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively. IC50 value: 0. 3 nM (Ki, CB1R) 21 nM (Ki, CB2R)Target: CB1Rin vivo: CB1 IN 1 is a novel peripherally restricted cannabinoid 1 receptor antagonist with significant weight loss efficacy in diet induced obese mice. CB1 IN 1 has great potential to ameliorate this related metabolic syndrome. Product information CAS