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(E)-Daporinad (FK866)-induced cell death is associated with inhibition of Nampt activity
and lipid biosynthesis during the last 2 h of the incubation is determined
PubMed PMID: 23002019
IC50 value: 9
InChi: InChI=1S/C6H8O2/c1-4-5(7)2-3-6(4)8/h4H
MARK-IN-2 renaline (E)-Daporinad (FK866)-induced cell death isMARK IN 2 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of 5 nM. Product information CAS Number: 1314893 26 9 Molecular Weight: 425. 88 Formula: C18H18ClF2N5OS Chemical Name: N [(1R,6R) 6 amino 2,2 difluorocyclohexyl] 4 {6 chloropyrazolo[1,5 a]pyrimidin 3 yl} 5 methylthiophene 2 carboxamide Smiles: CC1SC(=CC=1C1C=NN2C=C(Cl)C=NC2=1)C(=O)N[C@@H]1[C@H](N)CCCC1(F)F InChiKey: NGFGTMFVWSDFPS UKRRQHHQSA N InChi: InChI=1S