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If you have Sangan equipped with Blast with Chain and Sangan is destroyed in battle, Blast with Chain will be destroyed when Sangan leaves the field, but its secondary effect will not activate

This includes triggers that look for when permanents die (which is simply shorthand for is put into a graveyard from play) or are destroyed (shorthand for dies due to lethal damage, including deathtouch damage, or a destroy effect)

Hidegetsu deals half a player's life total rounded down, so when the two Creatures are used at the same time, any opponent with even life loses instantly

It is part of the meta Mewtwo EX deck

However, with such a simple and beneficial effect, Heat Factory was splashable on any deck that uses Fire-type energies as a resource