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29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9
Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors
2010 Sep 15
T<1 nM) followed by treatment with increasing concentrations of Galeterone (TOK-001)
a patient-derived tamoxifen-resistant xenograft tumor
MS 154N Size:2mg solid 29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9MS 154N is a negative control for MS 154. The compound exhibits high binding affinity for WT and L858R mutant EGFR (Kd values are 3 and 4. 3 nM, respectively), but does not significantly induce degradation of EGFR mutants. Product information Molecular Weight: 915. 45 Formula: C47H56ClFN8O8 Chemical Name: 3 (4 (3 ((4 ((3 chloro 4 fluorophenyl)amino) 7 methoxyquinazolin 6 yl)oxy)propyl)piperazin 1 yl) N (8 ((2 (1 methyl 2,6 dioxopiperidin 3 yl) 1,3
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