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Dorzolamide Hydrochloride Size:Solid 10 mg InChiKey: RXSARIJMSJWJLZ-CIAYNJNFSA-N

SKU: 44789697824

4.5
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Description

InChiKey: RXSARIJMSJWJLZ-CIAYNJNFSA-N

whereas the absence of P-gp causes a 6-fold increase in the plasma concentration and 3-fold higher brain-to-plasma concentration ratio after oral administration

Chemical Name: 2-benzyl-6

25-5 μM) blocks cell cycle progression in G2/M phase

it is rapidly degraded to its inactive form by thymidine phosphorylase in the intestines and liver (first-pass effect)

Dorzolamide Hydrochloride Size:Solid 10 mg InChiKey: RXSARIJMSJWJLZ-CIAYNJNFSA-NDorzolamide (trade name Trusopt) is a carbonic anhydrase inhibitor. It is an anti glaucoma agent and topically applied in the form of eye drops. This drug, developed by Merck, was the first drug in human therapy (market introduction 1995) which resulted from structure based drug design. Dorzolamide hydrochloride is used to lower increased intraocular pressure in open angle glaucoma and ocular hypertension. The combination of dorzolamide with timolol

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