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AG-490 potently inhibits IL-2-mediated human T cell growth with an IC50 of 25 μM by blocking the activities of JAK3 and STAT5a/b
blocks the interaction between the KIX domain and the KID domain of CREB with IC50 of 2
4-tetrazol-5-amine
InChiKey: SLRYMOUSQMDJPH-UHFFFAOYSA-N
InChiKey: CXGGTGCHTQMBOC-UHFFFAOYSA-N
L-Carnitine-d9 O5192 AG-490 potently inhibits IL-2-mediated humanL Carnitine d9 is the deuterium labeled L Carnitine. L Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L lysine and L methionine, as substrates. L Carnitine functions to transport long chain fatty acyl CoAs into the mitochondria for degradation by oxidation. L carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism. Product
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