Pinkie Pie has another ability, though: Any time you cast a spell where the art shows a smile, you get a tapped Treasure token
Now the only way an opponent could evade infect damage would be to always have a chunk blocker ready, exile Plague Myr, or enchant it with a Pacifism-type aura to prevent it from attacking and blocking
I've been playing Akiri, Fearless Voyager for years as my own Equipment commander specifically to encourage myself to Go Wide swinging with equipment instead of going Voltron as a self-imposed nerf to the deck and STILL it ends up correct to just pile on all my equipment on to a single creature most of the time
At least one of our opponents is always going to offer a nice discount on our beefy 6/6, flying, trample, haste Dragon
First is Titania, Gaea Incarnate, the melded combination of Titania, Voice of Gaea and Argoth, Sanctum of Nature