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The Master, Transcendent is one of the most recognizable villains from Fallout, so of course it had to be here somewhere

They're difficult to remove, pack a punch, and have unique effects that synergize with your deck

However, a few (like Isochron Scepters ability) instruct you to copy a spell and cast the copy. These spells are cast and will count toward the number of spells cast that turn

Any "as [this artifact] enters the battlefield" or "[this artifact] enters the battlefield with" abilities of the artifact will also work

Your best bet to pull it off is to play a commander like Selenia, Dark Angel that allows you to lose life on demand or have cards like Wall of Blood in play