667(1-3):153-9
The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation
InChi: InChI=1S/C66H110N15O20P/c1-4-5-6-7-8-9-10-11-12-13-14-28-53(83)70-39-54(84)73-43(22-15-16-33-67)58(89)74-45(30-32-55(85)86)57(88)71-41(2)62(93)80-37-20-26-50(80)65(96)78-35-18-24-48(78)60(91)72-42(3)63(94)81-38-21-27-51(81)66(97)79-36-19-25-49(79)61(92)75-44(29-31-52(68)82)59(90)76-46(40-101-102(98
5 nM for MCH1R and MCH2R
51)7)74-46-40(77-44-34(62)32(60)30(58)24(19-54)72-44)38(36(64)39(76-46)42(68)69)75-43(37(65)41(66)67)71-21-29(56)57/h8
Ketoconazole-d8 - CAS# 1217706-96-1 tetrazine-PEG5-NHS ester 667(1-3):153-9Ketoconazole d8 is the deuterium labeled Ketoconazole. Ketoconazole (R 41400) is an imidazole anti fungal agent, a CYP3A4 and CYP24A1 inhibitor. Product information CAS Number: 1217706 96 1 Molecular Weight: 539. 48 Formula: C26H28Cl2N4O4 Chemical Name: 1 [4 (4 {[(2R,4S) 2 (2,4 dichlorophenyl) 2 [(1H imidazol 1 yl)methyl] 1,3 dioxolan 4 yl]methoxy}phenyl)(2,2,3,3,5,5,6,6 H)piperazin 1 yl]ethan 1 one Smiles: