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InChiKey: MTJLQTFHJIHXIX-GDUXWEAWSA-N
Formula: C2H7NS
Harnessing Allostery: A Novel Approach to Drug Discovery[J]
with IC50 values of between 2
Molecular Weight: 732
Metolazone uolin-1 InChiKey: MTJLQTFHJIHXIX-GDUXWEAWSA-NMetolazone is a thiazide like diuretic. It is primarily used to treat congestive heart failure and high blood pressure. Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney, so that blood volume decreases and urine volume increases. This lowers blood pressure and prevents excess fluid accumulation in heart failure. Metolazone is sometimes used together with loop diuretics such as furosemide or bumetanide,
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