Early on, you're happy to throw something away to get the mana, and later on you hopefully don't need the Chrome Mox anymore
It can be daunting to determine values in a changing market, so it quickly becomes time to call in the professionals
Take Back the Power
It doesn't matter whether you have 0 or less life, you're forced to draw a card while your library is empty, you have ten or more poison counters, you're at the end of your Nine Lives, your opponent is a Triskaidekaphile, and so on
If you use it to exile a threatening commander, your opponent will either be forced to wait it out, denying them access to the creature they built their entire deck around for three whole turns, or they put it in the command zone, in which case its Swords to Plowshares minus the life gain