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It inhibits TCF/β-catenin mediated transcription by competing with β-catenin for CBP (CREB binding protein) but not p300 binding with an IC50 of 3 µM
Smiles: CN(C)CCSSCCNC(=O)C1CCN(CC1)C(=O)CSC1C=CC(Cl)=CC=1
InChiKey: IWQURBSTAIRNAE-KBXIAJHMSA-N
McN-JR 3345
Aegeline also prevents growth block in cells expressing the more toxic A53T α-synuclein mutant
1, 2-Dioleoyl-sn-glycero-3-phosphocholine Catalog No.:M28267-C It inhibits TCF/β-catenin mediated transcription1,2 Dioleoyl sn glycero 3 phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes. Product information CAS Number: 4235 95 4 Molecular Weight: 786. 11 Formula: C44H84NO8P Chemical Name: (2 {[(2R) 2,3 bis[(9Z) octadec 9 enoyloxy]propyl phosphonato]oxy}ethyl)trimethylazanium Smiles: C[N+](C)(C)CCOP([O ])(=O)OC[C@@H](COC(=O)CCCCCCC