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3(1):68-81
XL-647 YE-687 3(1):68-81Tesevatinib, also known as XL647, EXEL 7647 and KD 019, is a n orally bioavailable small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. XL647 binds to and inhibits several tyrosine receptor kinases that play major roles in tumor cell proliferation and tumor vascularization, including epidermal growth factor receptor (EGFR; ERBB1), epidermal growth factor receptor 2 (HER2; ERBB2), vascular endothelial growth
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