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5R)-2-carbamoyl-7-oxo-1
In pentobarbitone or ethyl carbamate-anaesthetized animals
LY3200882 shows potent anti-tumor activity in the orthotopic 4T1-LP model of triple negative breast cancer and this activity correlated with enhanced tumor infiltrating lymphocytes in the tumor microenvironment[1]
Dyatkina N
45(8):2348-2353
INT-777 - CAS# 1199796-29-6 HM-12 5R)-2-carbamoyl-7-oxo-1INT 777 is a semisynthetic bile acid that acts as an agonist of TGR5 (EC50 = 0. 82 M). INT 777 mitigates inflammatory response in human endometriotic stromal cells: A therapeutic implication for endometriosis. Product information CAS Number: 1199796 29 6 Molecular Weight: 450. 65 Formula: C27H46O5 Synonym: S EMCA INT777 INT 777 Chemical Name: (2S,4R) 4 [(1R,3aS,3bR,4R,5R,5aS,7R,9aS,9bS,11S,11aR) 5 ethyl 4,7,11 trihydroxy 9a,11a dimethyl hexadecahydro