FK 866 hydrochloride emodin InChiKey: GRZXWCHAXNAUHY-NSISKUIASA-N

InChiKey: GRZXWCHAXNAUHY-NSISKUIASA-N

57(10):4333-40

Ro-51 suffers rapid clearance

dog) is estimated to be 1

9(3):268-273

FK 866 hydrochloride emodin InChiKey: GRZXWCHAXNAUHY-NSISKUIASA-NFK 866 hydrochloride is an inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase) with IC50 values ranging between 0. 09nM and 27. 2nM . NAD plays a vital role in numerous biochemical and biologic processes. Targeting NAD synthesis is thought to be a selective manner to kill cancer cells since cancer cells have a higher rate of NAD turnover compared with normal cells. In the vitro MTT assay using a panel of 41 human hematologic cancer cell