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Solubility: DMSO : 110 mg/mL (251
is a pyrrolidinone-type cognition enhancer that has been clinically used in the treatment of behavioral and psychological symptoms of dementia following stroke and in Alzheimer's disease
and causes a 50-day survival rate of 60% and 50%
InChi: InChI=1S/C14H18BrN3O2/c15-11-1-3-12(4-2-11)17-13(19)9-18-7-5-10(6-8-18)14(16)20/h1-4
Formula: C135H222O116
Tebanicline hydrochloride Size:Contact [email protected] for quotation Solubility: DMSO : 110 mg/mLTebanicline hydrochloride (ABT594 hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. It inhibits the binding of cytisine to 42 neuronal nAChRs with a Ki of 37 pM. Tebanicline is a novel, potent cholinergic nAChR ligand with analgesic properties that shows preferential selectivity for neuronal nAChRs. It inhibits the binding of cytisine to 42 neuronal nAChRs with a Ki of 37 pM. Functionally, tebanicline is an agonist.
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