Pay in 4 interest-free payments of $12.25 Learn more
Ships within 48 hours · Estimated delivery Jul 30 - Aug 4
It has >100-fold selectivity over other methyltransferases and other non-epigenetic targets
1-6-2-4-7(5-3-6)11(8
AGI-5198 has good cellular activities in TS603 glioma cell line
1627676-59-8
(2011) J Pharmacol Exp Ther
OTX015 - BET Inhibitor. CAS# 202590-98-5 size:2 mg solid It has >100-fold selectivity overOTX015, CAS No. 202590 98 5, is a novel, highly potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3 and BRD4 with IC50 of 10 19 nM. It inhibits the growth of a variety of human cancer cell lines with IC50 ranging from 60 to 200 nM. OTX015 results in rapid down regulation of c MYC expression, and show the synergistic anti proliferative effects in combination with ALK inhibitors in ALKpos