Ailanthone Size:Contact [email protected] for quotation 43(1):222-35

43(1):222-35

and augmented animal survival

Regulated necrosis and its implications in toxicology

binds to AdipoR1 and AdipoR2

InChiKey: SPYIETQLOVDJCF-WQLSENKSSA-N

Ailanthone Size:Contact [email protected] for quotation 43(1):222-35Ailanthone (AIL, 13 Dehydrochaparrinone), a natural anti hepatocellular carcinoma (HCC) component in Ailanthus altissima, induces G0 G1 phase cell cycle arrest by decreasing expression of cyclins and CDKs and increases expression of p21 and p27. Ailanthone triggers DNA damage characterized by activation of the ATM ATR pathway. Ailanthone induces apoptosis which is mitochondrion mediated and involves the PI3K AKT signaling pathway in Huh7 cells.