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ABT-888 dihydrochloride inhibits the PARP activity with EC50 of 2 nM in C41 cells
BLT-1 is a specific inhibitor of the SR-BI (Scavenger receptor
NVP-BEZ235 and NVP-BGT226
Schächtele C
Ackerman J
ACT-132577 Size:Solid 10 mg ABT-888 dihydrochloride inhibits the PARPAprocitentan, also known as ACT 132577, is an endothelin receptor antagonist and an pharmacologically active metabolite of macitentan. Aprocitentan antagonized the specific binding of ET 1 on membranes of cells overexpressing ET(A) and ET(B) receptors and blunted ET 1 induced calcium mobilization in various natural cell lines, with inhibitory constants within the nanomolar range. Product information CAS Number: 1103522 45 7 Molecular Weight: 546. 19
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