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1421448-26-1
Azacytidine
Epub 2013 Feb 1
a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo
Journal of Medicinal Chemistry (2020)
Valrubicin - CAS# 56124-62-0 123 1421448-26-1Valrubicin, CAS No. 56124 62 0, is a semisynthetic derivative of the antineoplastic anthracycline antibiotic doxorubicin. With a mechanism of action that appears to differ from doxorubicin, valrubicin is converted intracytoplasmically into N trifluoroacetyladriamycin, which interacts with topoisomerase II, stabilizing the complex between the enzyme and DNA; consequently, DNA replication and repair and RNA and protein synthesis are inhibited and the