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AMG 925 altirelin CAS Number: 59-98-3

SKU: 96866089739

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Description

CAS Number: 59-98-3

WITHDRAWN: Celecoxib for rheumatoid arthritis

non-competitive and highly selective against a panel of more than 340 other enzymes and receptors

is a bactericidal drug that inhibits bacterial DNA gyrase and topoisomerase IV

Its superior potency is associated with its increased enzyme residence time and prolonged cellular effects after washout

AMG 925 altirelin CAS Number: 59-98-3FLX925, also known as AMG 925, is a potent and selective type 1 inhibitor of FLT3 that retains its cellular potency against clinically relevant secondary resistance mutations in FLT3 occurring with quizartinib or sorafenib treatment (FLX925 IC50: MOLM13ITD, 15 nM; MOLM13ITD D835, 28 nM; MV4 11ITD, 16 nM; MV4 11ITD D835, 19 nM; MV4 11ITD N841, 16 nM; MV4 11ITD F691, 73 nM). Product information CAS Number: 1401033 86 0 Molecular Weight: 471. 55 Formula:

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