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GJ071 and GJ072 and some of their analogs (such as GJ103) have similar read-through activity as RTC13 or RTC14
Genipin 1-β-D-gentiobioside (Genipin gentiobioside) has moderate terminal elimination half-life (t1/2=1
NSC-105327
3)4/h5-6H2
DDO-5936 shows limited oral efficiency
F-1 Catalog No.:M26247-C GJ071 and GJ072 and someF 1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho ALK and its relative downstream signaling pathways, with IC50s of 2. 1 nM, 2. 3 nM, 1. 3 nM and 3. 9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. Product information CAS Number: 2244775 31 1 Molecular Weight: 519. 02 Formula: C22H27ClN8O3S Chemical Name: N {2 [(5 chloro 2 {[2 methoxy 6 (4 methylpiperazin 1 yl)pyridin 3 yl]amino}pyrimidin 4