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AVN-492 displays great 5-HT6R selectivity against all other serotonin receptor subtypes
) dose-dependently increases extracellular DA in mPFC
13±0 and 58±9 nM for JAK1
Bosentan blocks the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure
mini-pump or parenteral once-weekly dosing
Azido-PEG11-alcohol 3-gentiobioside AVN-492 displays great 5-HT6R selectivityAzido PEG11 alcohol is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2252392 53 1 Molecular Weight: 527. 61 Formula: C22H45N3O11 Chemical Name: 32 azido 3,6,9,12,15,18,21,24,27,30 decaoxadotriacontan 1 ol Smiles: [N ]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO InChiKey: QBBFWGPQBOSPDN UHFFFAOYSA N InChi: InChI=1S C22H45N3O11 c23 25 24 1 3 27 5 7 29 9 11 31 13 15 33 17 19 35 21 22 36 20 18 34 16 14