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Cosgrove SB
250-fold selectivity vs human D3R
is a second-generation pyrrolo-pyrimidine designed to enhance selectivity towards the Src family relative to other cytoplasmic tyrosine kinases
is an investigational drug candidate for metastatic colorectal cancer
no degradation in CRBN null Molt4 cells at any concentration (0
NCX 4040 PC-(C3-PEG)2-C6-Cl Cosgrove SBProduct information CAS Number: 287118 97 2 Molecular Weight: 331. 28 Formula: C16H13NO7 Chemical Name: 4 [(nitrooxy)methyl]phenyl 2 (acetyloxy)benzoate Smiles: CC(=O)OC1=CC=CC=C1C(=O)OC1C=CC(CO[N+]([O ])=O)=CC=1 InChiKey: CTHNKWFUDCMLIQ UHFFFAOYSA N InChi: InChI=1S C16H13NO7 c1 11(18)23 15 5 3 2 4 14(15)16(19)24 13 8 6 12(7 9 13)10 22 17(20)21 h2 9H,10H2,1H3 Technical Data Appearance: Solid Power Purity: 98% (or refer to the Certificate of Analysis)
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