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InChi: InChI=1S/C13H14N8O2/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2
activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis
γ-Tocopherol (D-γ-Tocopherol) is well absorbed and accumulates to a significant degree in some human tissues
3-c]pyridine-5-carboxylate
Triazolotriazine derivatives as a2a receptor antagonists
YKL-5-124 TFA Catalog No.:M14492-2 InChi: InChI=1S/C13H14N8O2/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2YKL 5 124 TFA is a potent, selective, irreversible and covalent CDK7 inhibitor with IC50s of 53. 5 nM and 9. 7 nM for CDK7 and CDK7 Mat1 CycH, respectively. YKL 5 124 TFA is >100 fold greater selective for CDK7 than CDK9 and CDK2, and inactive against CDK12 and CDK13. YKL 5 124 TFA induces a strong cell cycle arrest, inhibits E2F driven gene expression, and exhibits little effect on RNA polymerase II phosphorylation status. Product information
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