GSK-25 - CAS# 874119-56-9 60275 CAS Number: 301326-22-7

CAS Number: 301326-22-7

Smiles: C1CNCCN1C1C=CC(=CC=1)C1=CN2N=CC(=C2N=C1)C1=CC=CC2=NC=CC=C21

Smiles: O=C(NC1=CC(Br)=CC=C1)C1=CC(=CC=C1)S(=O)(=O)N1CCCCCC1

T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer

p38 and Akt signalling in C2C12 cells

GSK-25 - CAS# 874119-56-9 60275 CAS Number: 301326-22-7GSK 25, CAS No. 874119 56 9, is a potent, selective and orally bioavailable ROCK1 inhibitor (IC50=7 nM). GSK 25 maintains good selectivity against a panel of 31 kinases (>100 fold), as well as RSK1 and p70S6K (RSK1: IC50=398 nM, p70S6K: IC50=1 M). GSK 25 inhibits P450 profile (IC50s of 2. 5, 5. 2, 2. 5 M for CYP2C9, CYP2D6, CYP3A4, respectively). Product information CAS Number: 874119 56 9 Molecular Weight: 513. 33 Formula: C24H16Cl2F2N6O Chemical