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GCN2-IN-1 Catalog No.:M27762-C Galiellalactone (10 μM) inhibits STAT3

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Description

Galiellalactone (10 μM) inhibits STAT3 signaling activity as assessed by luciferase reporter gene assay in IL-6-stimulated LNCaP cells

blocks the inhibitory effect of clonidine with an pA2 value of 6

9 micrograms/ml

5)10-9-22(25)32)20(31)16-18-19-17-27(4

Protective effects of Salvia plebeia compound homoplantaginin on hepatocyte injury

GCN2-IN-1 Catalog No.:M27762-C Galiellalactone (10 μM) inhibits STAT3GCN2 IN 1 (A 92) is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with an IC50 of <0. 3 M in the enzyme assay and an IC50 of 0. 3 3 M in the cell assay. Product information CAS Number: 1448693 69 3 Molecular Weight: 402. 41 Formula: C19H18N10O Chemical Name: N [3 (1H indazol 6 yl) 3H [1,2,3]triazolo[4,5 d]pyrimidin 5 yl] 1 (oxan 4 yl) 1H pyrazol 4 amine Smiles: C1CC(CCO1)N1C=C(C=N1)NC1=NC2=C(C=N1)N=NN2C1=CC2NN=CC=2C=C1 InChiKey:

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