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ClH/c1-14-9-18(23)20(11-21(14)27)26-22-17-8-7-16(10-19(17)24-13-25-22)28-12-15-5-3-2-4-6-15
and displays a favorable cytotoxicity profile toward normal cells
3'-biindolylidene]-5'-sulfonic acid
it does cause drowsiness
Smiles: CN1CCN(CC2C=CC(=CC=2)C2=CN([C@@H]3CC[C@@H](O)CC3)C3=NC(NCCC4CC4)=NC=C23)CC1
EGFR-IN-5 - CAS# 2225887-26-1 0-Deacetylbaccatin III ClH/c1-14-9-18(23)20(11-21(14)27)26-22-17-8-7-16(10-19(17)24-13-25-22)28-12-15-5-3-2-4-6-15EGFR IN 5 is a EGFR inhibitor with IC50s of 10. 4, 1. 1, 34, 7. 2 nM for EGFR, EGFRL858R, EGFRL858R T790M, and EGFRL858R T790M C797S, respectively. Product information CAS Number: 2225887 26 1 Molecular Weight: 571. 69 Formula: C31H38FN9O Chemical Name: {1 [6 ({5 [4 (dimethylamino)piperidin 1 yl]pyridin 2 yl}amino) 2 [(4 fluorophenyl)amino]pyrido[3, 4 d]pyrimidin 4 yl]piperidin 4 yl}methanol Smiles:
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