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is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity
10H-Dipyrido(2
Formula: C24H25F3N6S
CAS Number: 77-52-1
25-trihydroxy-15-[(1R)-1-hydroxyethyl]-2
MRS 2578 Size:Solid 10 mg is a novel hydroxamic acid-typeMRS 2578 is a selective antagonist of P2Y6 nucleotide receptors (IC50 values are 37 and 98 nM at human and rat P2Y6 receptors respectively). Activation of P2Y6 receptor amplifies mucosal adenosine triphosphate release underlying bladder overactivity in patients with benign prostatic hyperplasia. Therefore, selective P2Y6 receptor blockade as a novel therapeutic strategy is potentially useful to control persistent storage symptoms in obstructed
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