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3 nM and 44
selective and high-affinity 5-HT2C receptor antagonist with a pKi of 9
in these two cancer cell lines (H1417 and H146 cell lines)
NMS-P715 accelerates mitosis and affects kinetochore components localization causing massive aneuploidy and cell death in a variety of tumoral cell lines and inhibits tumor growth in preclinical cancer models
33)29-10-8-28(6-2)9-11-29/h14-15H
PI3Kγ inhibitor 4 - CAS# 1821038-80-5 Size:Contact [email protected] for quotation 3 nM and 44PI3K inhibitor 4 is a potent, selective and orally active inhibitor of PI3K, with an IC50 of 40 nM. PI3K inhibitor 4 shows 7, 43, and 18 fold selectivity for PI3K over the , , and isoforms, respectively. PI3K inhibitor 4 can be used for the research of airway inflammation. Product information CAS Number: 1821038 80 5 Molecular Weight: 416. 49 Formula: C20H24N4O4S Chemical Name: 3 [6 amino 5 (2 methyl 1,3 oxazol 5 yl)pyridin 3 yl] N (2 hydroxy 2