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It can suppress HIV-1 replication and enhance cell viability in a HIV-1 infected T cell line
CX-5461 was administered orally at 50 mg/kg either once daily or every 3 days
It facilitates extinction and prevents reinstatement of cocaine-conditioned place preference
Formula: C30H40ClN7O3S
Chemical Name: (S)-N-((3R
Cyclopamine - Hedgehog Antagonist. CAS# 4449-51-8 0077 It can suppress HIV-1 replicationCyclopamine, CAS No. 4449 51 8, is a potent and selective inhibitor of the hedgehog signaling with an IC50 ~46 nM, acting as an antagonist of Smoothened. It is a natural product isolated from the corn lily (Veratrum californicum). As the hedgehog signaling pathway plays very important roles in embryogenesis and cancer progression, Cyclopamine has been used in stem cell differentiation, such as pancreatic cell differentiation from ESC iPSC, or treating