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7-Hydroxycoumarinyl arachidonate (7-HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2)
and significantly ehhances the inhibition via 10
InChi: InChI=1S/C17H20F2N2O/c1-17(2)5-3-11(4-6-17)20-16(22)15-9-12-13(19)7-10(18)8-14(12)21-15/h7-9
CC(C)C1C=NN2C=1N=C(N=C2N[C@H]1CC2C3=CC=CC=C3NC=2CC1)C1=CC(F)=CN=C1
CAS Number: 149155-45-3
Bax inhibitor peptide P5 xazide 7-Hydroxycoumarinyl arachidonate (7-HCA) is aBax inhibitor peptide P5 (BIP P5) is a peptide inhibitor of Bax translocation to mitochondria . Bax is a pro apoptotic member of Bcl 2 family proteins and plays an important role in mitochondria dependent apoptosis. Bax stays in the cytosol and transfers into mitochondria after apoptotic stimuli . BIP P5 is a membrane permeable peptide inhibitor of Bax translocation to mitochondria. In HeLa cells, BIP P5 protected cells from UVC and STS induced
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