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3 μM) or in the presence of ROT significantly reduces (S935)-LRRK2 kinase phosphorylation to control
InChi: InChI=1S/C21H18Br2N2O/c22-14-6-8-20-18(10-14)19-11-15(23)7-9-21(19)25(20)13-17(26)12-24-16-4-2-1-3-5-16/h1-11
1 GNAQ uveal melanoma xenograft model in a dose-dependently manner
MC1568 was used at 5-10µM final concentration in vitro and cellular assays
Entrectinib significantly inhibits the growth of TrkB-expressing NB cells in vitro
GW-7647 - CAS# 265129-71-3 60134 3 μM) or in theGW 7647, CAS No. 265129 71 3, is a potent, selective agonist of human and murine PPAR4 It activates human PPAR, PPAR, and PPAR with EC50 values of 0. 006, 1. 1 and 6. 2 M, respectively. Product information CAS Number: 265129 71 3 Molecular Weight: 502. 75 Formula: C29H46N2O3S Synonym: GW 7647 GW 7647 GW7647 Chemical Name: 2 ((4 (2 (3 cyclohexyl 1 (4 cyclohexylbutyl)ureido)ethyl)phenyl)thio) 2 methylpropanoic acid Smiles: