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a PKC substrate
which contributes to the induction of G2 arrest in GES-1 cells
Smiles: CC(C)(O)C(O)CC1C(OC)=C2C=CC(=O)OC2=CC=1OC
InChi: InChI=1S/C21H23Cl2NO6/c1-5-7-15(25)29-10-30-21(27)17-12(3)24-11(2)16(20(26)28-4)18(17)13-8-6-9-14(22)19(13)23/h6
Solubility: DMSO 77 mg/mL (199
N-Desmethyltamoxifen Catalog No.:M14339-2 a PKC substrateN Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N Desmethyltamoxifen, a poor antiestrogen, is a ten fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation. Product information CAS Number: 31750 48 8 Molecular Weight: 357. 49 Formula: C25H27NO Chemical
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