(R)-CR8 - CAS# 294646-77-8 Size:2mg solid Tamsulosin is an α1a adrenergic

Tamsulosin is an α1a adrenergic receptor antagonist used in the symptomatic treatment of benign prostatic hyperplasia (BPH)

C4H11N/c7-4-1-2-5(8)6(3-4)12(9

InChiKey: ODKNJVUHOIMIIZ-RRKCRQDMSA-N

Epub 2015 Aug 5

In higher concentrations

(R)-CR8 - CAS# 294646-77-8 Size:2mg solid Tamsulosin is an α1a adrenergic(R) CR8 (CR8), a second generation analog of Roscovitine, is a potent CDK1 2 5 7 9 inhibitor. (R) CR8 inhibits CDK1 cyclin B (IC50=0. 09 M), CDK2 cyclin A (0. 072 M), CDK2 cyclin E (0. 041 M), CDK5 p25 (0. 11 M), CDK7 cyclin H (1. 1 M), CDK9 cyclin T (0. 18 M) and CK1 (0. 4 M). (R) CR8 induces apoptosis and has neuroprotective effect[1][2]. (R) CR8 acts as a molecular glue degrader that depletes cyclin K. Product information CAS Number: 294646 77 8