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KL1333 011381 but had only a marginal

SKU: 89261854122

4.4
USD180.00 USD214.00

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Description

but had only a marginal effect in PC-12 cells and HL-60 cells

Smiles: C#CCOCCOCCOCCOCCOCC(=O)ON1C(=O)CCC1=O

3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors

1021/jm501436m

InChiKey: BQAVZGJJQFJSMW-UHFFFAOYSA-N

KL1333 011381 but had only a marginalKL1333, a derivative of lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H: quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin induced ototoxicity in mouse cochlear cultures. Product information CAS Number: 1800405 30 4 Molecular Weight:

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