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R-(+)-ETOMOXIR - CAS# 124083-20-1 093 379(1):115-20

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Description

379(1):115-20

Chemical Name: 1-(4-(6-methyl-5-(3

105(30):10595-600

MALT1-MI-2 (MI-2) was intraperitoneally (IP) dosed to mice at 25 mg/kg once per day for 14 days in TMD8 and HBL-1 ABC-DLBCL xenografts

CAS Number: 1369773-39-6

R-(+)-ETOMOXIR - CAS# 124083-20-1 093 379(1):115-20R (+) ETOMOXIR, CAS No. 124083 20 1, is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT 1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as

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