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DLK-IN-1 Size:Contact [email protected] for quotation InChiKey: LUKBXSAWLPMMSZ-OWOJBTEDSA-N

SKU: 8924647446

4.9
USD100.00 USD145.00

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Description

InChiKey: LUKBXSAWLPMMSZ-OWOJBTEDSA-N

Crossing the blood brain barrier

InChi: InChI=1S/C22H21N3O/c23-21(26)17-13-19(15-5-2-1-3-6-15)20(25-14-17)16-7-9-18(10-8-16)22(24)11-4-12-22/h1-3

This PET study supports the conclusion that the upregulation of genes in rats treated with 15 mg/kg Pridopidine are a result of specific activation of the S1R

InChiKey: ZCTCZKWJFTYNMZ-WKUCUCPSSA-J

DLK-IN-1 Size:Contact [email protected] for quotation InChiKey: LUKBXSAWLPMMSZ-OWOJBTEDSA-NDLK IN 1 is a selective, orally active inhibitor of dual leucine zipper kinase (DLK, MAP3K12), with a Ki of 3 nM. DLK IN 1 retains excellent CNS penetration and is well tolerated following multiple days of dosing at concentrations that exceed those required for DLK inhibition in the brain. DLK IN 1 has activity in a model of Alzheimers Disease. Product information CAS Number: 1620574 24 4 Molecular Weight: 423. 43 Formula: C20H24F3N5O2 Chemical Name:

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