PROTAC BRD4 Degrader-9 - CAS# 2417370-42-2 ic Acid (hydrate) InChi: InChI=1S/C36H36N4O4/c1-38-23-30(29-14-8-9-15-32(29)38)35(43)40-22-28(41)20-33(40)34(42)37-31(36(44)39(2)21-24-10-4-3-5-11-24)19-25-16-17-26-12-6-7-13-27(26)18-25/h3-18

Name: PROTAC BRD4 Degrader-9 - CAS# 2417370-42-2 ic Acid (hydrate) InChi: InChI=1S/C36H36N4O4/c1-38-23-30(29-14-8-9-15-32(29)38)35(43)40-22-28(41)20-33(40)34(42)37-31(36(44)39(2)21-24-10-4-3-5-11-24)19-25-16-17-26-12-6-7-13-27(26)18-25/h3-18
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Description

InChi: InChI=1S/C36H36N4O4/c1-38-23-30(29-14-8-9-15-32(29)38)35(43)40-22-28(41)20-33(40)34(42)37-31(36(44)39(2)21-24-10-4-3-5-11-24)19-25-16-17-26-12-6-7-13-27(26)18-25/h3-18

but eIF4A1 F163L mutation rescues eFT226 anti-proliferative activity

InChiKey: ZDASUJMDVPTNTF-UHFFFAOYSA-N

) causes nuclear translocation of ERRβ receptors in WT mice

Integrin modulator 1 increases cell adhesion mediated by α4β1 integrin

PROTAC BRD4 Degrader-9 - CAS# 2417370-42-2 ic Acid (hydrate) InChi: InChI=1S/C36H36N4O4/c1-38-23-30(29-14-8-9-15-32(29)38)35(43)40-22-28(41)20-33(40)34(42)37-31(36(44)39(2)21-24-10-4-3-5-11-24)19-25-16-17-26-12-6-7-13-27(26)18-25/h3-18PROTAC BRD4 Degrader 9 (compound 8a) is a PROTAC connected by ligands for von Hippel Lindau and BRD4. PROTAC BRD4 Degrader 9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0. 86 nM and 7. 6 nM, respectively. Product information CAS Number: 2417370 42 2 Molecular Weight: 1312. 50 Formula: C59H71F2N9O15S4 Chemical Name: (2S,4R) 1 [(2S) 2 (2 {2 [2 (2 {[8 (3,5 difluoropyridin 2

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