Leflunomide Catalog No.:M7673-10 KU-0063794 inhibits the phosphorylation of

KU-0063794 inhibits the phosphorylation of mTORC1 at Ser2448 and mTORC2 at Ser2481 in a dose-dependent and time-dependent manner

InChi: InChI=1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/h3-7

Formula: C16H16N8O

Co-incubation of pulmonary arterial smooth muscle cells (PASMCs) from the pulmonary arterial hypertension (PAH) rats with UK-92480 and LDN193189 completely inhibited the anti-proliferation and up-regulation of the bone morphogenetic protein (BMPR2) and Cx40 expression by the UK-92480

is a TKL family serine/threonine protein kinase involved in innate immune signaling

Leflunomide Catalog No.:M7673-10 KU-0063794 inhibits the phosphorylation ofLeflunomide (original brand name Arava) is an immunosuppressive disease modifying antirheumatic drug (DMARD), used in active moderate to severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase. Product information CAS Number: 75706 12 6 Molecular Weight: 270. 21 Formula: C12H9F3N2O2 Synonym: Arava Leflunomidum HWA 486 Chemical Name: 5 methyl N [4