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selective and orally active inhibitor of NLRP3 inflammasome
Recilisib (ON 01210) is a radioprotectant
JX06 (1-10 μM
OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication
13-hexaen-2-yl}propyl)(methyl)amino]-1-(4-chlorophenyl)ethan-1-one
Poly(I:C) oxyprogesterone acetate selective and orally active inhibitorSynthetic double stranded RNA (dsRNA); Toll like receptor 3 (TLR3) agonist. Aids generation of stable, mature dendritic cells in combination with TLR8 agonist CL 075. Transfection into NIT 1 cells induces cell apoptosis. Immunostimulant. Transfection of Poly (I: C) into NIT 1 cells has been used as a model of intracellular dsRNA induced cell apoptosis. Eighteen hours post transfection, 45% of the cells were apoptotic with an increase in NF kB, p50 p65
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