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Formula: C20H23BrN2O4
Daily oral dosing of 50 mg/kg Ponatinib causes significant tumor regression (%T/C = 0
Smiles: OC1=CC2NC(OC=2C(Br)=C1)=C1C=CC(=O)C=C1
PubMed PMID: 23921309
and selective acid pump antagonist for the treatment of gastroesophageal reflux disease
Urapidil Hydrochloride Size:Solid 10 mg Formula: C20H23BrN2O4Urapidil HCl is an antagonist of 1 adrenergic receptors (1 ARs) and a partial agonist of the serotonin (5 HT) receptor subtype 5 HT1A. Urapidil HCl inhibits cAMP accumulation induced by forskolin. It is also a 1 AR antagonist that inhibits the positive chronotropic response induced by isoproterenol. Urapidil HCl lowers mean arterial pressure (MAP) in anesthetized cats, an effect that is reduced by central administration of the 5 HT1A receptor