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ML281 is selectively toxic to KRAS-dependent cancer cell lines
Chemical Name: 3-{3-[(2E)-3
The sample was then centrifuged at 14000g for 10 min at 4-8 ℃
Lancet JE et al
4λ⁵-benzotriazine-1
MAT2A inhibitor 3 - CAS# 2439271-82-4 317 ML281 is selectively toxic toMAT2A inhibitor 3 is a methionine adenosyltransferase 2A (MAT2A) inhibitor extracted from patent WO2020123395A1, compound 24, has an IC50 of <200 nM. MAT2A inhibitor 3 can be used for the research of cancers. Product information CAS Number: 2439271 82 4 Molecular Weight: 299. 75 Formula: C16H14ClN3O Chemical Name: 7 chloro 4 (dimethylamino) 1 phenyl 1,2 dihydroquinazolin 2 one Smiles: CN(C)C1=NC(=O)N(C2=CC(Cl)=CC=C21)C1C=CC=CC=1 InChiKey: