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Intra-LC microinjection of orexin type-1 receptor antagonist SB-334867 attenuates the expression of glutamate-induced opiate withdrawal like signs during the active phase in rats
which does not suppress the activity of 93 other protein kinases including 13 AGC-kinases most related to PDK1 at 500-fold higher concentrations
And it significantly reduces apoptosis in cytokine-exposed cells ~10% at IL-1b concentrations above 15 pg/ml in rat insulin-producing INS-1 cells
Solubility: DMSO : 120 mg/mL (673
Formula: C23H20N6O
TP-3654 elivir mesylate hydrate Intra-LC microinjection of orexin type-1TP 3654 is a second generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim 1 and Pim 3, respectively. Product information CAS Number: 1361951 15 6 Molecular Weight: 418. 46 Formula: C22H25F3N4O Chemical Name: 2 [(1r,4r) 4 ({3 [3 (trifluoromethyl)phenyl]imidazo[1,2 b]pyridazin 6 yl}amino)cyclohexyl]propan 2 ol Smiles: CC(C)(O)[C@@H]1CC[C@H](CC1)NC1C=CC2=NC=C(C3=CC=CC(=C3)C(F)(F)F)N2N=1 InChiKey: XRNVABDYQLHODA JCNLHEQBSA N InChi:
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