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induces autophagy and apoptosis through promoting ROS/JNK activation
InChi: InChI=1S/C20H22O4/c1-5-6-13-9-15-12(2)19(24-20(15)18(10-13)23-4)14-7-8-16(21)17(11-14)22-3/h5-12
AML cell lines and primary samples are treated for 24 hours with C188-9
These actions are mediated by type 1 Ang II receptors (AT1)
and is also used to treat major depressive disorder (MDD)
BRD-6929 756 induces autophagy and apoptosis throughBRD 6929 is a potent, selective brain penetrant inhibitor of class I histone deacetylase HDAC1 and HDAC2 inhibitor with IC50 of 1 nM and 8 nM, respectively. BRD 6929 shows high affinity to HDAC1 and HDAC2 with Ki of 0. 2 and 1. 5 nM, respectively. BRD 6929 can be used for mood related behavioral model research. Product information CAS Number: 849234 64 6 Molecular Weight: 351. 42 Formula: C19H17N3O2S Chemical Name: N [2 amino 5 (thiophen 2 yl)phenyl]