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4 μM in C57BL/6 male mice
301836-41-9
is a potent and selective inhibitor of histone deacetylase 8 (HDAC8) with an IC50 ~10 nM
Orally active
656830-24-9
Fasudil Hydrochloride - CAS# 105628-07-7 Catalog No.:M6785-2 4 μM in C57BL/6 maleFasudil Hydrochloride, a potent Rho kinase inhibitor and vasodilator., CAS No. 105628 07 7, also known as HA 1077, is a potent Rho kinase inhibitor and vasodilator. Fasudil has been used for the treatment of cerebral vasospasm, which is often due to subarachnoid hemorrhage, as well as to improve the cognitive decline seen in stroke victims. It has been found to be effective for the treatment of pulmonary hypertension. It was demonstrated in February