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SBI-797812 1095 InChi: InChI=1S/C22H25FN6O4S

SKU: 85788032185

4.4
USD100.00 USD122.00

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Description

InChi: InChI=1S/C22H25FN6O4S

Formula: C31H38ClN7O7S2

Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC50 of 0

26)6-4-13)15-9-37-18(31-15)7-14(8-30-37)16(11-40-2)36-10-17(24(27

Bis-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs

SBI-797812 1095 InChi: InChI=1S/C22H25FN6O4SSBI 797812 is structurally similar to active site directed NAMPT inhibitors and blocks binding of these inhibitors to NAMPT with EC50 of 0. 37 M. SBI 797812 shifts the NAMPT reaction equilibrium towards NMN formation, increases NAMPT affinity for ATP, stabilizes phosphorylated NAMPT at His247, promotes consumption of the pyrophosphate by product, and blunts feedback inhibition by NAD+. Treatment of cultured cells with SBI 797812 increases

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